REACTIVITY OF WORKSHOP MONOCLONAL-ANTIBODIES WITH NORMAL AND PATHOLOGICAL OVINE LYMPH-NODES

Citation
M. Pepin et al., REACTIVITY OF WORKSHOP MONOCLONAL-ANTIBODIES WITH NORMAL AND PATHOLOGICAL OVINE LYMPH-NODES, Veterinary immunology and immunopathology, 39(1-3), 1993, pp. 249-267
Citations number
19
Categorie Soggetti
Immunology,"Veterinary Sciences
ISSN journal
01652427
Volume
39
Issue
1-3
Year of publication
1993
Pages
249 - 267
Database
ISI
SICI code
0165-2427(1993)39:1-3<249:ROWMWN>2.0.ZU;2-2
Abstract
The monoclonal antibodies (82 mAbs) included in the Second Workshop th at belonged to agreed named bovine CD and workshop clusters were teste d for their reactivity and tissue distribution on (1) normal sheep lym ph nodes and (2) pathological sheep lymph nodes. Pathological lymph no des were induced following experimental infection with Corynebacterium pseudotuberculosis and were characterized by the presence of typical pyogranulomas. Amongst the 82 mAbs tested, 38 reacted with sheep lymph nodes. The results of these tests are presented and discussed.