COMPARATIVE-STUDY OF SELECTIVE ALPHA-1-ADRENOCEPTOR BLOCKADE VERSUS SURGERY IN THE TREATMENT OF PROSTATIC OBSTRUCTION

Authors
CHAPPLE CR NOBLE JG MILROY EJG
Citation
Cr. Chapple et al., COMPARATIVE-STUDY OF SELECTIVE ALPHA-1-ADRENOCEPTOR BLOCKADE VERSUS SURGERY IN THE TREATMENT OF PROSTATIC OBSTRUCTION, British Journal of Urology, 72(5), 1993, pp. 822-825
Citations number
19
Categorie Soggetti
Urology & Nephrology
Journal title
British Journal of Urology → ACNP
ISSN journal
00071331
Volume
72
Issue
5
Year of publication
1993
Part
2
Pages
822 - 825
Database
ISI
SICI code
0007-1331(1993)72:5<822:COSABV>2.0.ZU;2-P
Abstract
Alternative treatments for benign prostatic hyperplasia (BPH) are the source of much discussion at present. Pharmacotherapy has been demonst rated to have an increasing role in the management of BPH. This study contrasts the efficacy of the selective alpha1 antagonist prazosin as compared with placebo and the subsequent improvements seen following s urgical treatment. Whilst selective alpha1 blockade has undoubted ther apeutic efficacy the improvement in symptom scores and the objective u rodynamic measure of the flow rate are not as marked as those seen fol lowing surgery.