THERMAL RESPONSE OF SYNCHRONOUS CHO CELLS WITH DIFFERENT SHAPES

Authors
SMITH NN HARVEY WF BEDFORD JS COSS RA
Citation
Nn. Smith et al., THERMAL RESPONSE OF SYNCHRONOUS CHO CELLS WITH DIFFERENT SHAPES, International journal of hyperthermia, 9(6), 1993, pp. 799-802
Citations number
18
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
International journal of hyperthermia → ACNP
ISSN journal
02656736
Volume
9
Issue
6
Year of publication
1993
Pages
799 - 802
Database
ISI
SICI code
0265-6736(1993)9:6<799:TROSCC>2.0.ZU;2-Z
Abstract
This study examines the differential heat sensitivity of rounded suspe nsion cells versus flattened monolayer cells. G1 populations of two di fferent Chinese hamster ovary lines were used to eliminate possible ce ll cycle artifacts. The cell populations were heated at 43 and 45-degr ees-C. In all cases, cells treated in suspension were less sensitive t o heat killing than cells treated as monolayers.