BIOMARKERS AND MOLECULAR EPIDEMIOLOGY OF OCCUPATIONALLY RELATED CANCER

Effective prevention of cancer requires sensitive early warning system s to identify groups, and ultimately individuals, who are at high risk of developing cancer and to accurately estimate the magnitude of thei r risk. Incorporated with molecular epidemiologic studies, biologic ma rkers have the potential to provide quantitative human data on the bio logically effective dose of carcinogens, resultant molecular effects, and genetic/acquired factors that modulate these effects. Clearly, thi s information is directly relevant to risk identification and to risk quantification.