FILTERING SURGERY WITH 5-FLUOROURACIL SUBSEQUENT TO MOLTENO IMPLANT

Authors
Citation
A. Ophir et U. Ticho, FILTERING SURGERY WITH 5-FLUOROURACIL SUBSEQUENT TO MOLTENO IMPLANT, Israel journal of medical sciences, 29(11), 1993, pp. 744-747
Citations number
26
Categorie Soggetti
Medicine, General & Internal
ISSN journal
00212180
Volume
29
Issue
11
Year of publication
1993
Pages
744 - 747
Database
ISI
SICI code
0021-2180(1993)29:11<744:FSW5ST>2.0.ZU;2-J
Abstract
In cases of refractory glaucoma, when Molteno shunt implantation has b een performed and resulted in failure, the best surgical option has no t yet been established. Filtering surgery with 5-fluorouracil (5-FU) a s one option for the above was performed in four non-neovascular glauc omatous eyes (four patients) after failure of Molteno shunt implantati on. Injections of 5 mg 5-FU were administered once daily for 9-14 days . After follow-up of 6-18 months in 3 eyes, intraocular pressure range d from 10 to 16 mm Hg. In the fourth eye, in which bleb scarring ensue d, a second filtering surgery with 5-FU was performed after 4 months, and resulted in a successful outcome as recorded 26 months later. Thes e preliminary results suggest that filtering surgery with 5-FU might b e an acceptable surgical option in non-neovascular refractory glaucoma subsequent to failure of Molteno shunt implantation.