STRUCTURE OF THE HUMAN PROGESTERONE-RECEPTOR GENE

Authors
MISRAHI M VENENCIE PY SAUGIERVEBER P SAR S DESSEN P MILGROM E
Citation
M. Misrahi et al., STRUCTURE OF THE HUMAN PROGESTERONE-RECEPTOR GENE, Biochimica et biophysica acta, 1216(2), 1993, pp. 289-292
Citations number
36
Categorie Soggetti
Biophysics,Biology
Journal title
Biochimica et biophysica acta → ACNP
ISSN journal
00063002
Volume
1216
Issue
2
Year of publication
1993
Pages
289 - 292
Database
ISI
SICI code
0006-3002(1993)1216:2<289:SOTHPG>2.0.ZU;2-J
Abstract
The complete organization of the human progesterone receptor (hPR) gen e has been determined. It spans over 90 kbp and contains eight exons. The first exon encodes the N-terminal part of the receptor. The DNA bi nding domain is encoded by two exons, each exon corresponding to one z inc finger. The steroid binding domain is encoded by five exons. The n ucleotide sequence of 1144 bp of the 5' flanking region has been deter mined.