Jm. Frigerio et al., THE PANCREATITIS ASSOCIATED PROTEIN-III (PAP-III), A NEW MEMBER OF THE PAP GENE FAMILY, Biochimica et biophysica acta, 1216(2), 1993, pp. 329-331
A third member of the rat pancreatitis associated protein (PAP) gene f
amily is described here. Its messenger RNA was cloned from an intestin
al cDNA library and sequenced. The encoded protein, designated PAP III
, shows 66% and 63% identity with the rat PAP I and II, respectively.
The PAP III gene is constitutively expressed in the small intestine an
d in the pancreas with acute pancreatitis, but not in the healthy panc
reas.