Increasing efforts are being made to improve drug-use practices and pr
escribing behaviour in developing countries. An essential tool for suc
h work is an objective and standard method of assessment. We present h
ere a set of drug-use indicators produced and tested in twelve develop
ing countries. We describe practical applications, which include the u
se of indicators to increase awareness among prescribers in Malawi and
Bangladesh, to identify priorities for action (eg, polypharmacy in In
donesia and Nigeria, overuse of injections in Uganda, Sudan, and Niger
ia, and low percentage of patients who understood the dosage schedule
in Malawi), and to quantify the impact of interventions in Yemen, Ugan
da, Sudan, and Zimbabwe.