METABOTROPIC GLUTAMATE RECEPTORS - AN ORIGINAL FAMILY OF G-PROTEIN-COUPLED RECEPTORS

Authors
BOCKAERT J PIN J FAGNI L
Citation
J. Bockaert et al., METABOTROPIC GLUTAMATE RECEPTORS - AN ORIGINAL FAMILY OF G-PROTEIN-COUPLED RECEPTORS, Fundamental and clinical pharmacology, 7(9), 1993, pp. 473-485
Citations number
81
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Fundamental and clinical pharmacology → ACNP
ISSN journal
07673981
Volume
7
Issue
9
Year of publication
1993
Pages
473 - 485
Database
ISI
SICI code
0767-3981(1993)7:9<473:MGR-AO>2.0.ZU;2-S
Abstract
In 1985, we discovered a new glutamate receptor which was coupled to p hospholipase C via a G protein and which was later termed metabotropic glutamate receptor (mGluR). In this review, both the diversity of mGl uRs and the cellular events they control are discussed, as well as the ir roles in physiological regulation and brain function.