ADENOSINE-DEAMINASE, 5' NUCLEOTIDASE, XANTHINE-OXIDASE, SUPEROXIDE-DISMUTASE, AND CATALASE ACTIVITIES IN CANCEROUS AND NONCANCEROUS HUMAN LARYNGEAL TISSUES

We determined activities of adenosine deaminase (ADA), 5' nucleotidase (5NT), xanthine oxidase (XO), superoxide dismutase (Cu-Zn SOD), and c atalase (CAT) enzymes in 15 human laryngeal tissues with well-differen tiated squamous cell carcinomas, in 15 corresponding tumor-free adjace nt tissues and in 7 normal laryngeal tissues. We found lower ADA and 5 NT and higher XO, Cu-Zn SOD, and CAT activities in cancerous tissues t han those in corresponding noncancerous ones. In the correlation analy sis, we established one positive intercorrelation, which was between A DA activities of tumor tissues and noncancerous adjacent tissues. We a lso found some significant intracorrelations between enzyme activities of the tissues, all of which were positive in cancerous ones.