MYOCLONIC SPASMS DURING TREATMENT WITH HIGH-DOSES OF INTRAVENOUS MORPHINE IN RENAL-FAILURE

Authors
SJOGREN P DRAGSTED L CHRISTENSEN CB
Citation
P. Sjogren et al., MYOCLONIC SPASMS DURING TREATMENT WITH HIGH-DOSES OF INTRAVENOUS MORPHINE IN RENAL-FAILURE, Acta anaesthesiologica Scandinavica, 37(8), 1993, pp. 780-782
Citations number
14
Categorie Soggetti
Anesthesiology
Journal title
Acta anaesthesiologica Scandinavica → ACNP
ISSN journal
00015172
Volume
37
Issue
8
Year of publication
1993
Pages
780 - 782
Database
ISI
SICI code
0001-5172(1993)37:8<780:MSDTWH>2.0.ZU;2-3
Abstract
Myoclonic spasms occurred in a patient suffering from renal failure af ter high doses of continuous intravenous morphine (100 mg/h). The conc entrations of morphine, morphine-6-glucuronide and morphine-3-glucoron ide (mumol/l) in plasma were: 1.93, 52.06 and 381.8, and in cerebrospi nal fluid were: 1.02, 5.86 and 61.82, respectively. The role of morphi ne and morphine glucuronides in myoclonic spasms is discussed.