THE ASSOCIATION BETWEEN SUPPLEMENTARY ESTROGEN intake and periodontal
and gingival status in a total of 228 women 50 to 64 years of age was
examined. Clinical parameters including visible supragingival plaque,
subgingival calculus, probing pocket depth, clinical attachment level,
alveolar bone height measurements, and number of remaining teeth were
measured. Gingival status was recorded as gingival bleeding after gen
tle manipulation. Selected periopathogens, socio-economic, demographic
, smoking habits, and health care variables were assessed. Gingival bl
eeding was significantly lower in the estrogen supplement group (n = 5
7) compared to the control group (n = 171) (P = 0.009); the estrogen g
roup also exhibited significantly lower visible plaque levels (P = 0.0
30) and fewer Capnocytophaga-ssp. (P = 0.032). Dental care was more fr
equent (P < 0.001), and education levels were higher (P = 0.022) in th
e estrogen group. To investigate whether differences among the above p
arameters contributed to the difference in gingival bleeding, an age-a
djusted analysis of covariance (ANCOVA) was used. The final ANCOVA ind
icated non-significant relationships for all parameters examined excep
t estrogen intake (P = 0.044). Women taking estrogen exhibited lower g
ingival bleeding than the control group after correcting for these fac
tors. The results indicate that estrogen supplementation is associated
with less gingival bleeding in women aged 50 to 64, as compared to an
age-matched control group.