PURPOSE: A prospective study was performed to compare results of compu
ted tomography (CT) and fiberoptic bronchoscopy in diagnosis of cancer
in patients with hemoptysis. MATERIALS AND METHODS: Ninety-one patien
ts (64 men, 27 women) with hemoptysis underwent thin-section CT and fi
beroptic bronchoscopy. RESULTS: CT scans demonstrated all 27 tumors se
en at bronchoscopy and an additional seven, five of which were beyond
bronchoscopic range. In patients with normal chest radiographs, bronch
ial carcinoma was detected in 5% at both bronchoscopy and CT. In patie
nts with abnormal findings on radiographs, bronchoscopy allowed both l
ocation and histologic diagnosis in 78% of carcinomas but was unreliab
le in locating perpheral tumors demonstrated at CT. CT was insensitive
in demonstrating early mucosal abnormalities, bronchitis, squamous me
taplasia, and a benign papilloma, all detected at bronchoscopy. CONCLU
SION: The initial examination should be bronchoscopy when there is hig
h clinical suspicion of carcinoma and relevant radiographic abnormalit
y, and CT when strong clinical suspicion of carcinoma is not substanti
ated at bronchoscopy in patients with normal findings on chest radiogr
aphs.