PURPOSE: To improve a method of stereotaxic localization with digital
subtraction angiography that does not require use of a localization fr
ame fixed to the patient's skull during examination. MATERIALS AND MET
HODS: An independent, low-cost, stereotaxic computing system was devis
ed. Software programs used magnetic resonance images, computed tomogra
phic scans, and digitized radiographs of plastic bone implants with he
ad landmarks to establish reference trihedrons in each imaging system,
transpose target coordinates from one system to another, adjust surgi
cal instruments, help plan radiation surgery, and compute and display
isodose curves. RESULTS: The geometric distortions of the image intens
ifier were corrected. Distortion problems of the conic projection were
solved, and three-dimensional localization was achieved with only two
associated front and lateral views. Accuracy to within 1 mm was achie
ved for the three coordinates. CONCLUSION: This frameless stereotaxic
localization technique is highly accurate and reliable. The system all
ows maximum automation of examination procedures.