CORNEOSCLERAL ULCERATION AND CORNEAL PERFORATION AFTER PTERYGIUM EXCISION AND TOPICAL MITOMYCIN-C THERAPY

A 78-year-old woman complained of ocular pain in the right eye. Thirty -three months before, the patient had a pterygium excised and mitomyci n C, 0.04%, was instilled 3 times a day postoperatively for 10 days in the right eye. The same surgery was performed and the same drug was u sed for a course of 5 days in the left eye. Corneoscleral ulceration a nd corneal perforation occurred in the right eye. The lesions were suc cessfully treated with a lamellar patch graft with reserved corneoscle ra. We believe that it may not be safe to instill 0.04% mitomycin C 3 times a day postoperatively for 10 days.