Mc. Desai et Lms. Stramiello, POLYMER-BOUND EDC (P-EDC) - A CONVENIENT REAGENT FOR FORMATION OF AN AMIDE BOND, Tetrahedron letters, 34(48), 1993, pp. 7685-7688
A facile preparation of polymer bound 1-ethyl-3-(3-dimethylaminopropyl
)carbodiimide (P-EDC) from commercially available starting materials i
s described. The P-EDC was found to be a convenient and general reagen
t for coupling of a variety of amines with diverse carboxylic acids.