A SHORT SERENDIPITOUS SYNTHESIS OF MINIMAL GLUCOCORTICOID RECEPTOR ZINC TEMPLATE

Authors
RANGANATHAN S JAYARAMAN N ROY R MADHUSUDANAN KP
Citation
S. Ranganathan et al., A SHORT SERENDIPITOUS SYNTHESIS OF MINIMAL GLUCOCORTICOID RECEPTOR ZINC TEMPLATE, Tetrahedron letters, 34(48), 1993, pp. 7801-7804
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
48
Year of publication
1993
Pages
7801 - 7804
Database
ISI
SICI code
0040-4039(1993)34:48<7801:ASSSOM>2.0.ZU;2-N
Abstract
The serendipitous formation of the novel, 20 membered, cyclo[bis-oxaly l cystine] - on treatment of cystine-di-OMe with oxalyl chloride - has provided an exceptionally short route to the first synthesis of the g lucocorticoid receptor zinc template via PDT mediated thiol-disulfide exchange and metal complexation.