REPRODUCIBILITY OF QUANTITATIVE ARTERIOGRAPHIC ASSESSMENT OF ATHEROSCLEROSIS IN THE FEMORAL-ARTERY

Citation
L. Bergstrand et al., REPRODUCIBILITY OF QUANTITATIVE ARTERIOGRAPHIC ASSESSMENT OF ATHEROSCLEROSIS IN THE FEMORAL-ARTERY, Acta radiologica, 34(6), 1993, pp. 612-617
Citations number
15
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
02841851
Volume
34
Issue
6
Year of publication
1993
Pages
612 - 617
Database
ISI
SICI code
0284-1851(1993)34:6<612:ROQAAO>2.0.ZU;2-W
Abstract
Results from computer-analysed angiograms in the Probucol Quantitative Regression Swedish Trial (PQRST) were analysed to determine the repro ducibility of the method and any drift in the analysing system. The pr ecision index (P(mu)) for 2 angiography series, made at 10 min interva ls, of the femoral artery in 276 patients was 10.5 for lumen volume an d 21.9 for roughness (edge irregularity). No difference in reproducibi lity was found between patients with and without symptoms of periphera l atherosclerosis or when looking at the reproducibility over years. A drift of 0.67% per year in the radiographic equipment (but not in the analysis system) was found, confirmed by use of phantoms. Computer-ba sed analysis of femoral atherosclerosis is a reliable method for follo w-up trials, giving high reproducibility even if the trial spans over several years and involves different centres. The use of phantoms is e ssential for checking the method over time.