TRANSLOCATION (Y 1)(Q12 Q21) IN ACUTE-LEUKEMIA

Citation
S. Singh et al., TRANSLOCATION (Y 1)(Q12 Q21) IN ACUTE-LEUKEMIA, Cancer genetics and cytogenetics, 70(2), 1993, pp. 136-139
Citations number
11
Categorie Soggetti
Oncology,"Genetics & Heredity
ISSN journal
01654608
Volume
70
Issue
2
Year of publication
1993
Pages
136 - 139
Database
ISI
SICI code
0165-4608(1993)70:2<136:T(1QIA>2.0.ZU;2-#
Abstract
This report documents one patient with myelodysplasia evolving into ac ute leukemia who showed a t(Y;1) translocation confirmed by in situ hy bridization. Most of the q arm of the Y chromosome was translocated to an additional q arm of chromosome 1, resulting in trisomy 1q. To our knowledge only four other cases with this t(Y;1) have been reported.