Sm. Moenter et al., CHARACTERIZATION AND REGULATION OF PREOVULATORY SECRETION OF GONADOTROPIN-RELEASING-HORMONE, Human reproduction, 8, 1993, pp. 51-56
Using an elegant method for sampling of pituitary portal blood the sec
retory characteristics of gonadotrophin-releasing hormone (GnRH) durin
g the oestradiol reduced surge are studied. It is demonstrated that th
e induced signal for ovulation in the ewe is a surge of GnRH released
into the portal blood.