BFA BODIES - A SUBCOMPARTMENT OF THE ENDOPLASMIC-RETICULUM

Authors
ORCI L PERRELET A RAVAZZOLA M WIELAND FT SCHEKMAN R ROTHMAN JE
Citation
L. Orci et al., BFA BODIES - A SUBCOMPARTMENT OF THE ENDOPLASMIC-RETICULUM, Proceedings of the National Academy of Sciences of the United Statesof America, 90(23), 1993, pp. 11089-11093
Citations number
45
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Proceedings of the National Academy of Sciences of the United Statesof America → ACNP
ISSN journal
00278424
Volume
90
Issue
23
Year of publication
1993
Pages
11089 - 11093
Database
ISI
SICI code
0027-8424(1993)90:23<11089:BB-ASO>2.0.ZU;2-7
Abstract
A specialized region of the endoplasmic reticulum-the BFA body-is defi ned by the site of accumulation of coatomer when nonclathrin coat prot ein (COP)-coated vesicle assembly is prevented by the drug brefeldin A (BFA). BFA bodies are formed by part smooth, part rough domains of en doplasmic reticulum that are cis to the classical transitional endopla smic reticulum and to BFA-induced Golgi remnants.