TOTAL SYNTHESIS OF PLUS-OR-MINUS)-17-BETA-HYDROXY-6-METHOXY-EQUILENINMETHYL-ETHER - A PROPOSED INTERMEDIATE FOR 11-OXO STEROID

Authors
MALLIK R CHATTERJEE A
Citation
R. Mallik et A. Chatterjee, TOTAL SYNTHESIS OF PLUS-OR-MINUS)-17-BETA-HYDROXY-6-METHOXY-EQUILENINMETHYL-ETHER - A PROPOSED INTERMEDIATE FOR 11-OXO STEROID, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(8), 1993, pp. 811-816
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
32
Issue
8
Year of publication
1993
Pages
811 - 816
Database
ISI
SICI code
0376-4699(1993)32:8<811:TSOP>2.0.ZU;2-L
Abstract
The known tricyclic ketone 4 has been efficiently utilised for the tot al synthesis of the title compound 1a, expected to serve as an advance d intermediate for 11-oxo steroid. Regioselective benzylic oxidation o f some model compounds such as 16a,b, unfortunately, affords the desir ed ketones 18a,b in low yields.