REDUCTION OF SUBSTITUTED ISOPROPYLIDENE METHYLENEMALONATES USING BOROHYDRIDE EXCHANGE RESIN

Authors
KANADE AS SAGAR AD SALUNKHE MM
Citation
As. Kanade et al., REDUCTION OF SUBSTITUTED ISOPROPYLIDENE METHYLENEMALONATES USING BOROHYDRIDE EXCHANGE RESIN, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(8), 1993, pp. 896-897
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
32
Issue
8
Year of publication
1993
Pages
896 - 897
Database
ISI
SICI code
0376-4699(1993)32:8<896:ROSIMU>2.0.ZU;2-M
Abstract
Substituted isopropylidene methylenemalonates (Knoevenagel type produc ts) (1-7) derived from Meldrum's acid (2,2-dimethyl-1,3-dioxan-4,6-dio ne) are readily reduced by borohydride exchange resin under mild react ion conditions to give 8-14 in high yields and in a state of high puri ty. The advantage of this method lies in its simplicity of performance , high yield of pure products and regeneration of resin to its initial activity in a single step.