We report the case of a 60-year old man who, during four years followi
ng surgical repair of an inguinal hernia (with transient antithromboti
c therapy), suffered from an atypical inflammatory nodule on the dorsu
m of the left foot with an erythematous plaque on the first intermetat
arsal space, together with an inflammatory plaque on the right fifth f
inger and hairless plaques on both wrists. An ultimate biopsy of the n
odule made it possible to discover, unexpectedly, two shadows of chole
sterol crystals in a vascular lumen and inside the cytoplasm of a gian
t multinucleate cell found on a single histological slice and at the d
eepest part of the fragment. The inflammatory lesions disappeared unde
r a 250 mg/day aspirin treatment. We emphasize the uncommon clinical a
nd pathological pseudo-lymphomatous features of this case and regard o
ur description as original in view of the chronicity of the embolising
process.