ALTERED SEXUAL-BEHAVIOR WITH MULTIPLE-SCLEROSIS - A CASE-REPORT

Hypersexuality and paraphilic behavior have been associated with a var iety of focal brain lesions but have rarely been documented in multipl e sclerosis (MS). We describe a woman with neuropathologically confirm ed MS who developed multiple paraphilias, disinhibition, and hypersexu ality prior to her death. The patient had extensive lesions involving basal frontal, perithalamic, septal, hypothalamic and temporal regions . Lesions that involve the frontal lobes and diencephalic structures i nfluence sexual behavior.