Recent decades have seen a dramatic increase in creative work on scien
tific ignorance and uncertainty, which can be traced in part to a real
ization that ignorance and uncertainty cannot always be reduced or ban
ished from science, and that they are social and cultural products rat
her than merely ''part of the phenomenon. '' The fact that ignorance i
s negotiable and yet fundamental to scientific work poses several impo
rtant dilemmas and prospects. We may be participating in a shift from
the traditional research strategies of reducing or banishing ignorance
toward a deeper understanding of and greater capacity to cope with ig
norance.