AUTOMATED GENETIC REGISTER AND COMPUTER S UPPORT FOR PHYSICIANS DIAGNOSIS

Computer-based genetical register <<GENREG>> allows to carry out a pro phylactic medical examination for families with children, having hered itary diseases, multifactorial pathology and congenital developmental defects of various nature, and also epidemiological examination. Autom ated consultative system for prelaboratorial diagnosis of genetically determined diseases after the phenotypical manifestations <<DIAGEN>> a llows to identify up to 1200 nosologic units; diagnostic value (or wei ght) of the signs according to physician's evaluation is taken into co nsideration. The system sorts out a narrow differetial-and-diagnostic row and information about specific laboratorial and functional changes for every selected diagnosis. Efficiency of the system is over 94% (a fter the next laboratorial findings). The results of computer diagnosi s and final physician's diagnosis, and also questionnaire of a child a re stored in archives (files) of the <<(DIAGEN>> system. Both of the s ystems are realized on PC/AT IBM-compatible computer.