A MORPHOLOGICAL BIOSENSOR FOR MAMMALIAN-CELLS

Authors
GIAEVER I KEESE CR
Citation
I. Giaever et Cr. Keese, A MORPHOLOGICAL BIOSENSOR FOR MAMMALIAN-CELLS, Nature, 366(6455), 1993, pp. 591-592
Citations number
11
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Nature → ACNP
ISSN journal
00280836
Volume
366
Issue
6455
Year of publication
1993
Pages
591 - 592
Database
ISI
SICI code
0028-0836(1993)366:6455<591:AMBFM>2.0.ZU;2-0
Abstract
An electrical biosensor is described that can continuously track morph ological changes of adherent cells providing quantitative data from bo th sparse and confluent cultures. The method is capable of detecting v ertical motion of cells of the order of 1 nm, much below the resolutio n of an optical microscope.