Fw. Fitzke et Br. Masters, 3-DIMENSIONAL VISUALIZATION OF CONFOCAL SECTIONS OF IN-VIVO HUMAN FUNDUS AND OPTIC-NERVE, Current eye research, 12(11), 1993, pp. 1015-1018
A confocal scanning laser ophthalmoscope was used to image the human f
undus in vivo at a series of 32 sections from near the retinal surface
to deep within the optic nerve head. The optical sections were digiti
zed and aligned to compensate for eye movement during image acquisitio
n and stored on a computer. This registered stack of optical sections
was reconstructed using specialized computational software. The three-
dimensional volume rendering of the stack of optical sections results
in a new way to view the in vivo optic nerve in three dimensions. This
technique is of clinical importance since structural factors of the l
amina cribrosa of the optic nerve may be important in glaucomatous dam
age. There may be diagnostic potential in the in vivo observation of t
he three-dimensional structure of the optic nerve.