ACUTE SYSTEMIC HYPOXIA AND THE SURFACE ULTRASTRUCTURE AND MORPHOLOGICAL-CHARACTERISTICS OF RAT LEUKOCYTES

Authors
MIAN R WESTWOOD D STANLEY P MARSHALL JM COOTE JH
Citation
R. Mian et al., ACUTE SYSTEMIC HYPOXIA AND THE SURFACE ULTRASTRUCTURE AND MORPHOLOGICAL-CHARACTERISTICS OF RAT LEUKOCYTES, Experimental physiology, 78(6), 1993, pp. 839-842
Citations number
6
Categorie Soggetti
Physiology
Journal title
Experimental physiology → ACNP
ISSN journal
09580670
Volume
78
Issue
6
Year of publication
1993
Pages
839 - 842
Database
ISI
SICI code
0958-0670(1993)78:6<839:ASHATS>2.0.ZU;2-S
Abstract
We have examined the surface ultrastructure and morphological characte ristics of leucocytes obtained from control rats breathing air and rat s made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrast ructural and morphological changes occurred in the leucocytes of hypox ic rats. These changes included die appearance of crater-like holes, a reduction in granule size and disruption of the cell membrane. The im plications of these findings are discussed.