LACK OF ASSOCIATION BETWEEN IMMUNOGLOBULIN LIGHT-CHAIN CONSTANT-REGION AND VARIABLE-REGION POLYMORPHISMS (C-KAPPA, V-KAPPA-II, V-LAMBDA-VIIAND VHIII) AND RHEUMATOID-ARTHRITIS

Authors
SIDEBOTTOM D BATE AS GRENNAN DM
Citation
D. Sidebottom et al., LACK OF ASSOCIATION BETWEEN IMMUNOGLOBULIN LIGHT-CHAIN CONSTANT-REGION AND VARIABLE-REGION POLYMORPHISMS (C-KAPPA, V-KAPPA-II, V-LAMBDA-VIIAND VHIII) AND RHEUMATOID-ARTHRITIS, Experimental and clinical immunogenetics, 10(3), 1993, pp. 129-136
Citations number
34
Categorie Soggetti
Genetics & Heredity",Immunology,Biology
Journal title
Experimental and clinical immunogenetics → ACNP
ISSN journal
02549670
Volume
10
Issue
3
Year of publication
1993
Pages
129 - 136
Database
ISI
SICI code
0254-9670(1993)10:3<129:LOABIL>2.0.ZU;2-#
Abstract
Restriction fragment length polymorphisms (RFLPs) of Ckappa, VkappaII, VlambdaVII and VHIII genes were studied from a pool of 104 subjects w ith rheumatoid arthritis and 96 controls. There were no overall associ ations with either rheumatoid arthritis itself, or with HLA-DR4-positi ve and DR4-negative RA subgroups within rheumatoid subjects in this UK Caucasoid population.