Sj. Goldman et al., PSYCHOPATHOLOGY IN THE FAMILIES OF CHILDREN AND ADOLESCENTS WITH BORDERLINE PERSONALITY-DISORDER, The American journal of psychiatry, 150(12), 1993, pp. 1832-1835
Objective: The purpose of this study was to determine whether rates of
psychopathology differed between the families of a group of children
and adolescents with borderline personality disorder and the families
of a psychiatric comparison group.- Method: The rates of psychiatric d
isorders in the families of 44 child and adolescent outpatients with b
orderline personality disorder were compared with the rates in the fam
ilies of a psychiatric comparison group of 100 children and adolescent
s, none of whom had a diagnosis of borderline personality disorder. Ps
ychopathology in family members was ascertained by the family history
method with the use of information from semistructured interviews with
the subjects in the two study groups and with their parents or guardi
ans. The adults were systematically interviewed regarding specific DSM
-III-R disorders in their families. Results: The families of the patie
nts with borderline personality disorder had significantly greater rat
es of psychopathology, particularly in the areas of depressive, substa
nce abuse, and antisocial disorders. Conclusions: The finding of highe
r rates of psychopathology among the family members of the group with
borderline personality disorder supports the hypothesis that a history
of significant family psychopathology is associated with the disorder
.