The effects of time gain control, nonlinear compression, beam diffract
ion, and nonuniform bandpass characteristic in an ultrasonic imaging i
nstrument are compensated by video signal processing to calculate regi
onal ultrasonic attenuation under a narrow-band assumption. Compensati
on for time gain control and amplitude compression is accomplished usi
ng a measurement of the digitized output value as a function of the ti
me gain control. Compensation for beam diffraction is performed using
the scattering from a random medium reference. Compensation for nonuni
form bandpass characteristics employs a measurement of the relative am
plitude response over the attenuation-induced frequency downshift expe
rienced by the signal. The decay of the compensated signal envelope wi
th range yields an attenuation value which is assigned to the nominal
centre frequency of the instrument. The method is applied to calculate
the attenuation in a model random medium using multiple views to obta
in an attenuation of 4.0 +/- 0.5 dB/cm at 3.5 MHz in the relatively sm
all region of 1.6 x 1.5 cm2. The calculations of attenuation value are
within 5% of the value obtained using a radiation force balance syste
m. The results indicate that video signal processing and multiple view
s can be used to quantify attenuation in regions of about 2 cm2 with a
n accuracy of the order of 10%.