The extent to which hospital-based pharmacists provide ambulatory clin
ical pharmacy services in-the United States is unknown. We evaluated p
harmacists' activities in hospital-affiliated ambulatory clinics and h
ome health services. A questionnaire was mailed to directors of pharma
cy in one-half of the United States acute care general medical-surgica
l hospitals with 50 or more licensed beds. The survey response rate wa
s 56% (n=1174). In 19% of hospitals, pharmacists provided patient care
(nondispensing activities) in ambulatory clinics. The most common cli
nics with pharmacist involvement were diabetes (10% of hospitals), onc
ology (9%), cardiology (6%), and geriatrics, infectious disease, and p
ain (4% each). Nondispensing roles varied by clinic type; prescribing
by protocol was performed in 57% of anticoagulation clinics and 7% of
diabetes clinics. Home health care services, with pharmacists' activit
y extending beyond providing drugs, were offered by 28% of the hospita
ls. Thirty-six percent of the hospitals operated one or more outpatien
t pharmacies. A statistically significant association was observed bet
ween hospitals' inpatient clinical pharmacy services (as assessed by t
he pharmaceutical care index) and the involvement of pharmacists in bo
th ambulatory clinics and home health care services.