Suramin, a drug used to treat parasitic diseases, is currently being i
nvestigated as a treatment for metastatic prostate cancer. A 73-year-o
ld man had an anaphylactoid reaction following the first dose of suram
in. It was treated successfully with epinephrine, diphenhydramine, and
hydrocortisone. Investigators should be aware of the possibility of s
uch a reaction with parenteral administration of this drug.