EXTRASKELETAL MYXOID CHONDROSARCOMA - A CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF 2 CASES

Two extraskeletal myxoid chondrosarcomas arising on the left lower ext remity of two women, aged 48 and 72 years, respectively, are reported. One case mimicked clinically an organized hematoma. By light microsco py, they showed a lobular architecture. Anastomosing cords of cells ly ing in a myxoid background were the histologic hallmark. Based on conv entional criteria, they were classified as neoplasms of low (G1) and i ntermediate (G2) grade malignancy. Both cases were strongly positive f or S-100 protein and vimentin. Follow-up confirmed the low aggressiven ess of this entity.