Primary adenosquamous carcinoma of the colon is a rare entity. Its pre
valent site of origin is at the level of the proximal portion of the l
arge bowel. The tumor presents in young patients and follows a highly
aggressive course. We present an extremely unusual case of adenosquamo
us carcinoma in which the classical mucinous and signet-ring cell aden
ocarcinoma was associated with the,squamous component. The prognosis o
f this rare neoplasm is very poor.