Rs. Sangwan et al., BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA, Phytochemistry, 34(5), 1993, pp. 1301-1302
In Artemisia annua, [C-14]arteannuic acid was incorporated into artean
nuin-B as well as artemisinin, both in vivo and in a cell free system.
Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations
under in vitro conditions. The results suggest that arteannuic acid m
ight be a common precursor for arteannuin-B and artemisinin synthesis.