THE EFFECTS OF TAURINE ON PERFUSED HEART-MUSCLE MALONDIALDEHYDE LEVELS

Authors
KAPLAN B ARICIOGLU A ERBAS D ERBAS S TURKOZKAN N
Citation
B. Kaplan et al., THE EFFECTS OF TAURINE ON PERFUSED HEART-MUSCLE MALONDIALDEHYDE LEVELS, General pharmacology, 24(6), 1993, pp. 1411-1413
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
General pharmacology → ACNP
ISSN journal
03063623
Volume
24
Issue
6
Year of publication
1993
Pages
1411 - 1413
Database
ISI
SICI code
0306-3623(1993)24:6<1411:TEOTOP>2.0.ZU;2-Q
Abstract
1. Taurine is found as a free amino acid in plasma and many tissues su ch as heart, muscle, brain and blood. Its exact role is not fully defi ned but it appears to have an important effect on the function of the heart. 2. The purpose of this study was to investigate the effects of taurine (10(-3) M and 10(-2) M) on malondialdehyde levels in perfused heart muscle. 3. In this study we found that administrated taurine bef ore anoxia and reperfusion increased the malondialdehyde levels but ad ministrated taurine after anoxia decreased the malondialdehyde levels in perfused heart muscle compared to the taurine administrated group b efore anoxia. 4. Anoxia did not change the perfused heart muscle malon dialdehyde levels.