VIRUS INACTIVATION BY COPPER OR IRON IONS ALONE AND IN THE PRESENCE OF PEROXIDE

Cupric and ferric ions were able to inactivate five enveloped or nonen veloped, single- or double-stranded DNA or RNA viruses. The virucidal effect of these metals was enhanced by the addition of peroxide, parti cularly for copper(II). Under the conditions of our test, mixtures of copper(II) ions and peroxide were more efficient than glutaraldehyde i n inactivating phiX174, T7, phi6, Junin, and herpes simplex viruses. T he substances described here should be able to inactivate most, if not all, viruses that have been found contaminating medical devices.