A. Kawado et al., YEAST SPORULATION INDUCED BY LYSINE DURING GROWTH IN NUTRITION-RICH CONDITIONS, Journal of fermentation and bioengineering, 76(5), 1993, pp. 391-394
Sporulation of the yeast Saccharomyces cerevisiae 4011 and other strai
ns of S. cerevisiae was induced by D- or L-lysine during growth in a n
utrient-rich medium. Potassium acetate was not required for the sporul
ation. The effects of other D- or L-amino acids on sporulation, if any
, were negligible or very slight. Although the sporulation efficiency
varied depending on the yeast strain, lysine concentration, pH of the
medium and incubation period, the results obtained indicated that nutr
itional starvation is not a prerequisite for the sporulation of yeast
cells, and that lysine or a certain cellular molecule involved in the
metabolism of the amino acid has the ability to cause meiosis and spor
ulation in yeast cells.