Background: The interpretation of spirometric results requires referen
ce values. Up to the moment, the reference values used in Chile are th
ose of Knudson et al, obtained in a white North American population st
udied in Tucson, USA. Aim: To obtain reference spirometric values from
a Chilean population. Subjects and methods: Maximal expiratory flow-v
olume curves were obtained from a randomly selected population of 850
healthy non-smoking subjects living at sea level, in cities without at
mospheric pollution. Equipment and techniques were used according to t
he recommendations of the American Thoracic Society. Results: Linear r
egression equations were obtained, using age and height as independent
variables and spirometric values as dependent variables, for both sex
es and ages from 6 to 70 years old. Our values for forced vital capaci
ty and forced expiratory volume were 9 to 18% and 10 to 15% higher tha
n those reported by Knudson et al. Conclusions: Chilean spirometric re
ference values differ from those used abroad, emphasizing the need to
use local standards to interpret spirometric results.