A. Wee et al., BILIARY CYSTADENOCARCINOMA ARISING IN A CYSTADENOMA - REPORT OF A CASE DIAGNOSED BY FINE-NEEDLE ASPIRATION CYTOLOGY, Acta cytologica, 37(6), 1993, pp. 966-970
Hepatic cyst fluid cytology tends to yield disappointing results. We r
eport a case of a 56-year-old woman with a biliary cystadenocarcinoma
diagnosed by fine needle aspiration cytology. Computed tomography scan
s had shown a solitary, unilocular hepatic cyst over a five-year perio
d. There was a recent increase in the size and development of a mural
echogenic focus. Cytologic examination revealed clusters of malignant
glandular cells in a background of cellular debris and mucinophages. T
he resected specimen confirmed the presence of an adenocarcinoma arisi
ng from malignant transformation of a pre-existing cystadenoma.