Mek. Ahmed et al., ACUTE UPPER GASTROINTESTINAL-BLEEDING IN SOUTHERN SAUDI-ARABIA, Journal of the Royal College of Physicians of London, 31(1), 1997, pp. 62-64
Objectives: to study the incidence of hospitalisation, causes, and out
comes of acute upper gastrointestinal bleeding (AUGIB) in southern Sau
di Arabia. Design and methods: prospective study of patients admitted
with AUGIB to a large district hospital in Abha City, southern Saudi A
rabia, between 1991 and 1993. All patients had upper endoscopy within
24 hours of admission. Results: AUGIB was the indication for upper end
oscopy in 240 (8.9%) of all upper gastrointestinal endoscopies (2,702)
. The patients' mean age was 44.3 years (SD 18.1; range 20-85 years).
The annual hospital admission rate for AUGIB was calculated as 31 per
100,000 population over the age of 20. The commonest causes were oesop
hageal varices (30%), gastritis and erosions (25%) and duodenal ulcers
(22%); gastric ulcers and malignancy were relatively uncommon. Liver
cirrhosis due to hepatitis B and C viruses was the main cause of bleed
ing oesophageal varices. Patients with variceal bleeding were younger
and had a higher mortality rate than nonvariceal bleeders. Conclusions
: bleeding oesophageal varices are the commonest cause of AUGIB in Sau
di Arabia owing to the endemicity of viral hepatitis B and C. The mort
ality from both variceal and non-variceal bleeding was lower than in w
estern countries probably because the patients are younger and because
of the relative rarity of malignancy and of the consumption of non-st
eroidal anti-inflammatory drugs.