Axillary masses are uncommon alterations when detected as an isolated
finding. We evaluated 31 patients with isolated axillary masses. Patie
nts with alterations of the breasts or the upper limbs or with ipsilat
eral chest lesions were excluded from the study. Nine patients had occ
ult breast cancer, 5 of them in the contralateral breast. Seven had me
tastatic lymph nodes of non-ductal origin, and 1 had carcinoma of apoc
rine cells with metastasis to the axilla. Four patients had benign lym
phadenopathy which disappeared spontaneously, and 4 others had rupture
d infundibular follicular cyst, nodular fibromatosis, inflammatory tub
erculous and inflammatory rheumatoid lymphadenitis. Five had an ectopi
c breast (2 with a fibroadenoma and 3 with fibrocystic changes). One p
atient had an axillary lipoma. The mean age of patients with malignant
pathology was 55.1 +/- 10.9 years, and the mean age of patients with
a benign pathology was 43.1 +/- 14.7 (P<0.01). Chest X-ray and bilater
al mammography are useful when the cause of the mass cannot be determi
ned by taking a detailed history of neoplastic or infectious anteceden
ts, by careful physical examination of the skin of the arms, trunk and
neck, or by palpation of the breasts and thyroid. Fine needle aspirat
ion biopsy distinguishes between benign and malignant pathologies. In
cases of indeterminate neoplasia, complete axillary dissection for dia
gnosis is indicated.