Aims and background: Recent data have suggested that cutaneous melanom
a in situ can be clinically recognized in most cases by its features,
which resemble those of early invasive melanoma. The aim of the study
was to verify whether the diagnostic sensitivity of melanoma in site i
s actually equivalent to that of early invasive melanoma. Methods: We
retrospectively reviewed the clinical diagnosis of 274 consecutive cut
aneous melanoma <0.75 mm thick. The series consisted of 84 in situ and
190 invasive lesions. Results: The clinical diagnosis of melanoma was
performed in 62% (52/84) of cases of in situ melanoma and in 68% (130
/190) of the cases of invasive melanoma. The differences were not stat
istically significant. Conclusions: Our results show that cutaneous me
lanoma can be clinically diagnosed at a very early stage. In situ and
very thin melanomas (< 0.75 mm) are similarly recognizable.