Ab. Russell et al., THE INFLUENCE OF VESSEL HEIGHT AND TOP-SECTION SIZE ON THE HYDRODYNAMIC CHARACTERISTICS OF AIRLIFT FERMENTERS, Biotechnology and bioengineering, 43(1), 1994, pp. 69-76
Fermentations of the yeast Saccharomyces cerevisiae were carried out i
n a 90 to 250-L working volume concentric tube airlift fermentor. Meas
urements of liquid circulation velocity, gas hold-up, and liquid mixin
g were made under varying conditions of gas flowrate, vessel height, a
nd top-section size. Both liquid circulation velocity and mixing time
increased with vessel height. Liquid velocity varied approximately in
proportion to the square root of column height, supporting a theoretic
ally based relationship. The effect of vessel height on gas hold-up wa
s negligible. The height of the top-section had a significant effect o
n liquid mixing. Mixing time decreased with increasing size of the top
-section up to a critical height. As the top-section was expanded beyo
nd this height, little improvement in mixing was seen. This indicated
the presence of a two-zone flow pattern in the top-section. Liquid vel
ocity and gas hold-up were essentially independent of top-section heig
ht. (C) 1994 John Wile & Sons Inc.