THE PRESENCE OF A CALCIUM-SENSITIVE P26-CONTAINING COMPLEX IN BOVINE RETINA ROD CELLS

Authors
GORODOVIKOVA EN PHILIPPOV PP
Citation
En. Gorodovikova et Pp. Philippov, THE PRESENCE OF A CALCIUM-SENSITIVE P26-CONTAINING COMPLEX IN BOVINE RETINA ROD CELLS, FEBS letters, 335(2), 1993, pp. 277-279
Citations number
18
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
335
Issue
2
Year of publication
1993
Pages
277 - 279
Database
ISI
SICI code
0014-5793(1993)335:2<277:TPOACP>2.0.ZU;2-D
Abstract
A protein with apparent M(r)26 kDa (p26[(1991) Biokimya 56, 225-228] o r recoverin [(1991) Science 251, 915-918]) was suggested to activate G C in a calcium dependent manner in bovine retina rod cells [(1991) Sci ence 251, 915-918;(1991) EMBO J, 10, 793-798] However, according to ou r present data homogeneous p26 preparations do not activate the enzyme . At the same time we have revealed a complex of p26 with an unidentif ied protein, presumably RK, in bovine ROS. Calcium favours formation o f the complex whereas EGTA addition (which corresponds to a low free C a2+ concentration) leads to its dissociation.