DIABETIC-PATIENTS WITH IGA NEPHROPATHY AND DIABETIC GLOMERULOSCLEROSIS

Eleven diabetic patients with biopsy-proven IgA nephropathy were studi ed. Seven exhibited coexistence of both IgA nephropathy and diabetic g lomerulosclerosis and the remaining four patients had IgA nephropathy without diabetic lesion. The clinicopathological features and follow-u p of those patients with IgA nephropathy surperimposed on diabetic glo merulosclerosis were compared with a similar group of patients with di abetic glomerulosclerosis alone. Our observation suggests that the occ urrence of both glomerulopathies was fortuitous with IgA nephropathy c oexisting with or preceeding diabetic glomerulosclerosis. There was no apparent causal relationship between the two glomerulopathies. The re nal outcome is poor in both groups of patients and is possibly related to diabetic glomerulosclerosis.