INFLUENCE OF NUTRIENT MEDIA ON THE COMPOSITION OF THE LYTIC ENZYMES COMPLEX OF STREPTOMYCES LEVORIS

A comparative investigation of the influence of casein, corn - soy-bea n, and corn fermentative media on the biosynthesis of lytic enzymes by Streptomyces levoris culture was made. The corn medium is shown to be most favorable for production of endo-N-acetylmuramidase, an enzyme u sed to obtain native biopolymers from the cell walls of streptococci a nd other Gram-positive bacteria. The medium ensured a 15 - 17-fold inc rease in the endo-N-acetylmuramidase yield, 4 - 5-fold increase in its specific lytic activity, and the simplification of its isolation from the culture liquid due to reduction of the component composition of t he lytic enzymes complex of S. levoris, i.e., to the decrease in ''bal last'' proteins content in the culture liquid.